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A dose of 0.5mg means 20 units

Important Note on the Evidence Base Important note on the evidence base: The clinical evidence on the IGF-1 axis derives largely from trials of recombinant human IGF-1 (rhIGF-1, sold as mecasermin / Increlex), which is FDA-approved for severe primary IGF-1 deficiency in pediatric patients

Increases in calcitonin levels have been observed in some patients, though the clinical significance remains uncertain