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When necessary, they were anesthetised with sodium pentobarbital (5 mg/kg mouse and 50 mg/kg rat body weight, i.p

Amplification of inflammation in emphysema and its association with latent adenoviral infection

Science 342 (6157), 1241006

Part of this comes from weight loss itself (excess adipose tissue actively produces inflammatory signals), and part appears to come from tirzepatides direct metabolic effects