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Maximum Responder Rate (20%+ Loss)# Recommendation : CagriSema Reason : 60% of CagriSema patients achieved at least 20% weight loss in REDEFINE 1, a higher responder rate than tirzepatide's across-trial data, though cross-trial comparison has limitations

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While tripeptides have been introduced as promising therapeutic agents in earlier sections, this part contrasts their therapeutic potential with larger peptides, based on their physicochemical characteristics and performance in wound healing models

Extended continuous daily administration risks progressive receptor desensitization that would diminish the compound's effectiveness over time