E6446 oxyguanosine c-Jun N-terminal kinase promotes stem

c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun

is a potent and long-acting DPP-4 inhibitor for once-weekly treatment of type 2 diabetes

Moscarella E

antiproliferative activity

E6446 oxyguanosine c-Jun N-terminal kinase promotes stemE6446 inhibits Toll like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA TLR9 interaction in vitro. When administered to mice, this compound suppress responses to challenge doses of cytidine phosphate guanidine (CpG) containing DNA, which stimulates TLR9. Product information CAS Number: 1219925 73 1 Molecular Weight: 449. 59 Formula: C27H35N3O3 Synonym: E 6446 Chemical Name: 6 [3 (pyrrolidin 1