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You should contact your GP or diabetes specialist nurse if: Hiccups persist for more than 48 hours despite self-care measures Hiccups are severe enough to interfere with eating, sleeping, or daily activities You experience hiccups alongside other concerning symptoms such as chest pain, difficulty breathing, or severe abdominal pain You develop signs of dehydration due to persistent vomiting (dry mouth, dark urine, dizziness) More serious gastrointestinal side effects associated with Mounjaro that require urgent medical assessment include: Severe, persistent abdominal pain, particularly if radiating to the back (potential sign of pancreatitis) Persistent nausea and vomiting preventing adequate fluid or food intake Signs of gallbladder problems, such as pain in the upper right abdomen, fever, or jaundice (yellowing of skin or eyes) Symptoms of severe gastroparesis, including early satiety, bloating, and vomiting undigested food You should also be aware of hypoglycaemia symptoms if you take Mounjaro alongside other diabetes medications, particularly insulin or sulphonylureas

The 0.5 mg dose of tesofensine slightly increased heart rate but did not significantly affect blood pressure

SURMOUNT-1 Jastreboff AM et al

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